Olfactory Receptor 2F1 (OR2F1)

The deduced 317-amino acid protein contains an extracellular N-terminal domain with a potential N-glycosylation site, 7 predicted transmembrane segments, and potential C-terminal phosphorylation sites. Human and canine OR2F1 share 86% identity. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.