Olfactory Receptor 9G9 (OR9G9)

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.OR9G9 is a close paralog of the OR9G1 that does occur in hg18. As a result, reads originating from OR9G9 may increase the measured depth-of-coverage of the OR9G1 locus. Therefore, the observed copy-number genotypes of ‘2’ and ‘3’ for the OR9G1 locus may in fact correspond to a copy-number genotype of ‘2’ for OR9G1 and copy-number genotypes of ‘0’ and ‘1’ for OR9G9. The deletion allele affecting OR9G9 is relatively common.