ATPase Class I Type 8B2 (ATP8B2)
Английские синонимы
ATPID; P4-ATPase flippase complex alpha subunit ATP8B2; Phospholipid-transporting ATPase ID
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. Alternatively spliced transcript variants encoding different isoforms have been identified.ATP8B2 is 53% identical to FIC1 (ATP8B1), which is associated with cholestasis. RT-PCR analysis detected wide expression, with highest levels in amygdala, followed by cerebellum, caudate nucleus, subthalamic nucleus, ovary, whole brain, and kidney.
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Московский государственный университет им. Ломоносова
Московский государственный университет им. Ломоносова
