Casein Kinase 1 Gamma 2 (CSNK1g2)

The casein kinase I (CKI) gene family encodes serine/threonine kinases that preferentially phosphorylate acidic substrates using ATP as a phosphate donor. CKI proteins are monomeric and range from 25 to 55 kD.Kitabayashi et al. (1997) isolated a clone of immature cDNA encoding human casein kinase I gamma-2 (CSNK1G2) by screening a human testis cDNA library with a PCR-amplified probe representing the kinase domain of rat casein kinase I gamma-2. The predicted amino acid sequence consists of 416 residues, 94% of which are identical to those of the rat homolog.Kitabayashi et al. (1997) mapped the human CSNK1G2 gene to 19p13.3 by fluorescence in situ hybridization and PCR analysis of a human/rodent hybrid cell panel.