Desumoylating Isopeptidase 1 (DESI1)
Английские синонимы
FAM152B; PPPDE2; Family With Sequence Similarity 152, Member B; PPPDE Peptidase Domain Containing Protein 2
Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibilitylocus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein, Bcr-Abl, a potent cell proliferation activator found in several types of leukemia. The PPPDE2 gene product has been provisionally designated PPPDE2 pending further characterization.
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С нами успешно сотрудничают:
Московский государственный университет им. Ломоносова
Московский государственный университет им. Ломоносова
