Exoribonuclease 2 (ERI2)

ERI2, Belongs to the ERI2 family.Contains 1 exonuclease domain. An exoribonuclease is an exonuclease ribonuclease, which are enzymes that degrade RNA by removing terminal nucleotides from either the 5""" end or 3""" end of the RNA molecule. Enzymes that remove nucleotides from the 5""" end are called 5"""-3""" exoribonucleases and enzymes that remove nucleotides from the 3""" end are called 3"""-5""" exoribonucleases. Exoribonucleases can use either water to cleave the nucleotide-nucleotide bond or inorganic phosphate. Hydrolytic exoribonucleases are classified under EC number 3.1 and phosphorolytic exoribonucleases under EC number 2.7.7. As the phosphorolytic enzymes use inorganic phosphate to cleave bonds they release nucleotide disphosphates, whereas the hydrolytic enzymes release nucleotide monosphosphates.