Glycerophosphodiester Phosphodiesterase Domain Containing Protein 2 (GDPD2)
Английские синонимы
OBDPF; GDE3; Osteoblast Differentiation Promoting Factor; Glycerophosphodiester phosphodiesterase 3; Glycerophosphoinositol inositolphosphodiesterase GDPD2
GDPD2 encodes a member of the glycerophosphodiester phosphodiesterase enzyme family. The encoded protein hydrolyzes glycerophosphoinositol to produce inositol 1-phosphate and glycerol. This protein may have a role in osteoblast differentiation and growth. Alternate splicing results in multiple transcript variants.GDPD2 has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4-phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton
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