N-Acylsphingosine Amidohydrolase 2C (ASAH2C)
Английские синонимы
Non-lysosomal ceramidase C; Putative neutral ceramidase C
Neutral ceramidase C also known as N-acylsphingosine amidohydrolase 2C or non-lysosomal ceramidase C or ASAH2C is a ceramidase enzyme encoded by the ASAH2C gene.Ceramidase is an enzyme which cleaves fatty acids from ceramide, producing sphingosine (SPH) which in turn is phosphorylated by a sphingosine kinase to form sphingosine-1-phosphate (S1P).Ceramide, SPH, and S1P are bioactive lipids that mediate cell proliferation, differentiation, apoptosis, adhesion, and migration. Presently, 7 human ceramidases encoded by 7 distinct genes.neutral ceramidase (ASAH2, ASAH2B, ASAH2C) – protective against inflammatory cytokines
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Московский государственный университет им. Ломоносова
Московский государственный университет им. Ломоносова
