SH3 Binding Domain Kinase 2 (SBK2)

SBK2 Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.Contains 1 protein kinase domain.Serine/threonine protein kinases phosphorylate the OH group of serine or threonine. At least 125 of the 500+ human protein kinases are serine/threonine kinases (STK).While serine/threonine kinases all phosphorylate serine or threonine residues in their substrates, they select specific residues to phosphorylate on the basis of residues that flank the phosphoacceptor site, which together comprise the consensus sequence. Since the consensus sequence residues of the substrate to be phosphorylated make contact with the catalytic cleft of the kinase at several key amino acids, a kinase is usually not specific to a single substrate, but instead can phosphorylate a whole "substrate family" having common recognition sequences.