TDP Glucose-4,6-Dehydratase (TGDS)
Английские синонимы
TDPGD; SDR2E1; Short Chain Dehydrogenase/Reductase Family 2E, Member 1; dTDP-D-glucose 4,6-dehydratase
TGDS belongs to the sugar epimerase family. dTDP-glucose dehydratase subfamily. In enzymology, a dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) is an enzyme that catalyzes the chemical reaction: dTDP-glucose <=>dTDP-4-dehydro-6-deoxy-D-glucose + H2OThis enzyme has one substrate, dTDP-glucose, and two products, dTDP-4-dehydro-6-deoxy-D-glucose and H2O.This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. This enzyme participates in 4 metabolic pathways: nucleotide sugars metabolism, streptomycin biosynthesis, polyketide sugar unit biosynthesis, and biosynthesis of vancomycin group antibiotics. It employs one cofactor, NAD+.
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Московский государственный университет им. Ломоносова
Московский государственный университет им. Ломоносова
