Ubiquitin Conjugating Enzyme E2U (UBE2U)

UBE2U belongs to the ubiquitin-conjugating enzyme family. Currently, UBE2U has only been found in mammalian cells. This ligase catalyzes the covalent attachment of ubiquitin to other proteins.the gene has been proposed to participate in processes. Proteins are expected to have molecular functions and to localize in nucleus. The gene contains 14 different gt-ag introns. Transcription produces 8 different mRNAs, 6 alternatively spliced variants and 2 unspliced forms. There are 3 probable alternative promotors, 5 non overlapping alternative last exons and 6 validated alternative polyadenylation sites. The mRNAs appear to differ by truncation of the 5""" end, truncation of the 3""" end, presence or absence of 3 cassette exons, overlapping exons with different boundaries.