Nucleoredoxin Like Protein 2 (NXNL2)

NXNL2, Belongs to the nucleoredoxin family. Contains 1 thioredoxin domain. the gene has been proposed to participate in a process. Proteins are expected to have molecular function. Nucleoredoxin splice variants in adult mouse tissues, with highest expression in testis and skin and lowest expression in liver. In situ hybridization showed that expression of nucleoredoxin varied during mouse embryonic development. Expression was widespread in embryos at days 9.5 and 10.5, with expression in limb buds, somites, dorsal root ganglia, branchial bars, and parts of the brain, but expression was marginal at day 12.5. Epitope-tagged nucleoredoxin localized to nuclei of transfected COS-7 cells. Southern blot analysis detected nucleoredoxin orthologs in human, rat, and rabbit, but not in frog, fly, nematode, and yeast.