Fatty Acid Binding Protein 10, Liver (FABP10)
Английские синонимы
fabp10a; L-BABP; L-FABP; Fatty acid-binding protein, liver; Liver bile acid-binding protein; Liver-type fatty acid-binding protein
The paralogous fabp10 gene encoding basic L-FABP, found to date in only nonmammalian vertebrates, was assigned to zebrafish linkage group 16. RT-PCR amplification of mRNA in adults, and in situ hybridization to whole-mount embryos to fabp1a, fabp1b and fapb10 mRNAs, revealed a distinct and differential pattern of expression for the fabp1a, fabp1b and fabp10 genes in zebrafish, suggesting a division of function for these orthogolous and paralogous gene products following their duplication in the vertebrate genome.The differential and complementary expression patterns of the zebrafish fabp1a, fapb1b and fabp10 genes imply a hierarchical subfunctionalization that may account for the retention of both the duplicated fabp1a and fabp1b genes, and the fabp10 gene in the zebrafish genome.
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Московский государственный университет им. Ломоносова
Московский государственный университет им. Ломоносова
