MAS Related GPR Member A (MRGPRA)
Английские синонимы
Mrga; Mas-related G-protein coupled receptor member A
MRGPRA, Belongs to the G-protein coupled receptor 1 family. Mas subfamily. Expressed in a subset of sensory neurons that includes nociceptors. Expressed in the subclass of non-peptidergic sensory neurons that are IB4+ and VR1-. Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.G protein-coupled receptors are found only in eukaryotes, including yeast, choanoflagellates, and animals. The ligands that bind and activate these receptors include light-sensitive compounds, odors, pheromones, hormones, and neurotransmitters, and vary in size from small molecules to peptides to large proteins. medicinal drugs.
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Московский государственный университет им. Ломоносова
Московский государственный университет им. Ломоносова
