Mitotic Spindle Organizing Protein 2A (MZT2A)

Using SDS-PAGE, Hutchins et al. (2010) found that MOZART2A had an apparent molecular mass of about 16.2 kD.Using gene tagging on BACs, protein localization, and tandem-affinity purification-mass spectrometry, Hutchins et al. (2010) showed that MOZART1 (C13ORF37), MOZART2A, and MOZART2B (FAM128B) copurified with subunits of the gamma-tubulin ring complex (gamma-TuRC), which is essential for spindle assembly and chromosome segregation.Hartz (2010) mapped the FAM128A gene to chromosome 2q21.1 based on an alignment of the FAM128A sequence with the genomic sequence (GRCh37).