DnaJ/HSP40 Homolog Subfamily C, Member 8 (DNAJC8)

DNAJC8 contains 1 J domain. PSORT analysis (a program that predicts the subcellular localization site of a given protein from its amino acid sequences) revealed that hDj9 has an N-terminal signal peptide; hence, its localization might be extracellular, suggesting that there may be a partner Hsp70 protein that acts together with the hDj9 outside of the cell. The same analysis indicated that mDj7 and mDj10 may have transmembrane domains. This proposed nomenclature includes the name of species with 2 lowercase letters such as Homo sapiens, Mus musculus and Rattus norvegicus; Dj standing for DnaJ; the name of types with A, B, and C, which were previously classified as type I, II, and III according to the domain structure of the homologs; and finally Arabic numerals according to the chronological order of registration of the sequence data into the database.