Chlorfenvinphos (CFP)

Chlorfenvinphos is the common name of an organophosphorus compound that was widely used as an insecticide and an acaricide. The molecule itself can be described as an enol ester derived from dichloroacetophenone and diethylphosphonic acid. Chlorfenvinphos is most commonly absorbed into the body through either ingestion of food products that have been treated with the pesticide, or through dermal absorption, though the latter is much less efficient. Once absorbed, chlorfenvinphos is widely distributed throughout the body, and has been detected in a variety of bodily fluids. However, as an organophosphorus compound, it does not accumulate well in tissues. The first and most important step of metabolism of chlorfenvinphos in humans is accomplished by the enzyme cytochrome P450 in liver microsomes.