Propylhexedrine (PHX)

Propylhexedrine is a stimulant drug used mainly to provide temporary symptomatic relief of nasal congestion due to colds, allergies and allergic rhinitis. Being a vasoconstrictor used to decongest nasal mucosa, it is administered by inhalation. Propylhexedrine is structurally similar to methamphetamine and other phenylethylamines, with the only structural difference being the substitution of an alicyclic cyclohexyl group for the aromatic phenyl group of phenethylamine. Propylhexedrine is not an amphetamine, nor even a phenethylamine, but instead can be referred to as a cycloalkylamine. Because propylhexedrine is not an amphetamine, it is somewhat less potent than structurally similar amphetamines such as methamphetamine.Propylhexedrine is a chiral compound, and active ingredient contained in Benzedrex inhalers is racemic (RS)-propylhexedrine as the free base.