Germ Cell Less Homolog 1 Like Proteim (GMCL1L)

GMCL1L contains 1 BTB (POZ) domain. Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport By similarity. Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.Gmcl1 is known to be a nuclear lamina protein. Gmcl1 is RIPA-insoluble, so it"""s likely mgclh will also be RIPA-insoluble. Protein size is expected to be around 55 kDa. The original literature on Gmcl1 said they resuspended the RIPA-insoluble pellet in "SDS-polyacrylamide gel electrophoresis sample buffer", but doesn"""t give the composition.