Histone Cluster 1, H1d (HIST1H1D)

HIST1H1D is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.By PCR analysis of chromosomal DNA from a panel of human/rodent somatic cell hybrids and by fluorescence in situ hybridization, Albig et al. (1993) demonstrated that 6 human H1 histone genes, including H1.3, are located on chromosome 6p22.2-p21.1. By analysis of a YAC contig, Albig et al. (1997) mapped the H1.3 gene to chromosome 6p21.3 within a cluster of 35 histone genes, including H1.1 (HIST1H1A) to H1.4 (HIST1H1E) and H1T (HIST1H1T). The H1.5 gene (HIST1H1B) is part of a separate subcluster within the same chromosomal region.