Inner Membrane Protein, Mitochondrial (IMMT)

Mitochondrial inner membrane protein is a protein encoded by the IMMT gene.The International Radiation Hybrid Mapping Consortium mapped the IMMT gene to chromosome 2p11.2.The heart muscle protein gene is expressed predominantly in the heart and is proposed to be an ATP-driven motor protein that interacts with cytoskeletal components. Icho et al. (1994) cloned a full-length 2.7-kb cDNA coding for a 758-amino acid protein. The protein has a possible ATP-binding domain at the N terminus and a long alpha-helical domain that could form a coiled-coil structure. Proteins with similar structures include myosin II , an actin-based motor protein, and kinesin, a microtubule-based motor protein