Syntrophin Alpha 1 (SNTa1)

Syntrophin is a peripheral membrane protein of relative mass approximately 58,000 that was first identified in the postsynaptic membrane of Torpedo electric organ and subsequently shown to be present in many mammalian tissues. Interest in syntrophin came first from its location at the neuromuscular junction and later from the demonstration that it is directly associated with dystrophin. A potential role for the dystrophin-associated proteins in agrin-stimulated nicotinic acetylcholine receptor clustering has implicated syntrophin in the process of synaptogenesis. Syntrophin,Alpha 1 is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.