Urinary Trypsin Inhibitor (UTI)

Ulinastatin is a glycoprotein which acts as a trypsin inhibitor. It may be effective in treatment of acute pancreatitis, chronic pancreatitis, toxic shock, Stevens–Johnson syndrome and toxic epidermal necrolysis (TEN). Urinary Trypsin Inhibitor is a glucoprotein proteinase inhibitor with a molecular weight of about 67,000 derived from human urine which inhibits the activity of trypsin, chymotrypsin, lactate, lipase, hyaluronidase and various pancreatic enzymes. Ulinastatin is effective for acute pancreatitis, chronic recurrent pancreatitis and hemorrhagic, traumatic and endotoxic shocks. Ulinastatin is has strong inhibition effect to various protease, sugar and fat hydrolase. Ulinastatin precursor is proteolytically processed into distinct functioning proteins. urinary trypsin inhibitor belongs to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes.