C1q And Tumor Necrosis Factor Related Protein 4 (C1QTNF4)

C1qTNF proteins constitute a highly conserved family of Acrp30/Adiponectin paralogs that share a modular organization comprising an N-terminal signal peptide, a short variable region, a collagenous domain and a C-terminal globular domain. C1qTNF proteins are predicted to have trimeric structures that assemble into hexameric and higher order molecular forms.C1QTNF4 is moderately expressed, only 31.4% of the average gene in this release.C1QTNF4 contains 2 different gt-ag introns. Transcription produces 2 alternatively spliced mRNAs. There are 2 validated alternative polyadenylation sites. The mRNAs appear to differ alternative splicing or retention of one intron. There is one article specifically referring to this gene in PubMed. Proteins are expected to localize in extracellular.