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Артикул
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Наименование |
Производитель
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|---|---|---|
| RHP09101 |
RHP09101
Anti-MCF2L2 Antibody (R4D34)
Источник (хозяин): мышь
Реактивность подтвержденная: человек
Валидировано для:
IHC
Производитель:AntibodySystem
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AntibodySystem |
MCF2 Cell Line Derived Transforming Sequence Like Protein 2 (MCF2L2)
Английские синонимы
ARHGEF22; DRG; Dbs-related Rho family guanine nucleotide exchange factor; Probable guanine nucleotide exchange factor MCF2L2
MCF2L2, ADIPOQ and SOX2 genes are located in chromosome 3q26-27, which is linked to diabetic nephropathy (DN). ADIPOQ and SOX2 genetic polymorphisms are found to be associated with DN.Leu359Ile T/G variant in the MCF2L2 gene was found to be associated with DN in female subjects but not in males. The GG genotype carriers among female patients with DN had tendency decreased creatinine and cystatin levels compared to the carriers with either TT or TG genotypes. MCF2L2, ADIPOQ and SOX2 genetic polymorphisms have effects on the resistance of DN in female T1D patients, and suggests that the linkage with DN in chromosome 3q may be explained by the cumulated genetic effects.
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С нами успешно сотрудничают:
Московский государственный университет им. Ломоносова
Московский государственный университет им. Ломоносова
