Wingless Type MMTV Integration Site Family, Member 2 (WNT2)

WNT2 is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins which are involved in the Wnt signaling pathway. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene.The INT1-related protein is an additional member of the INT1 growth factor gene family. Because of its homology to protooncogene INT1, IRP is also symbolized INT1L1. IRP is expressed in a variety of fetal and adult human tissues that do not overlap with the pattern of expression of INT1.