Adipogenesis Regulatory Factor (ADIRF)

APM2 (adipose most abundant gene transcript 2), also known as C10orf116, is a 76 amino acid protein that is expressed in liver, cornea and adipose tissue and is encoded by a gene which maps to human chromosome 10. Chromosome 10 houses over 1,200 genes and comprises nearly 4.5% of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.