Amiloride Sensitive Cation Channel Protein 5, Intestinal (ACCN5)

Amiloride Sensitive Cation Channel 5,Intestinal belongs to the amiloride-sensitive Na+ channel and degenerin (NaC/DEG) family, members of which have been identified in many animal species ranging from the nematode to human. The amiloride-sensitive Na(+) channel encoded by this gene is primarily expressed in the small intestine, however, its exact function is not known.Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum.Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride.