Armadillo Repeat Containing Protein, X-Linked 4 (ARMCX4)

The armadillo (ARM) repeat family of proteins are related to the Drosophila melanogaster armadillo protein, a protein essential for wingless signal transduction. ARM proteins are involved in a variety of processes such as cell migration, cell proliferation, tissue maintenance and tumorigenesis. They are intracellular proteins and function in signal transduction and cell structure. Members of the ARM family include ARMCX1, ARMCX2, ARMCX3, ARMCX4, ARMCX5 and ARMCX6. ARMCX6 (armadillo repeat containing, X-linked 6) is a 300 amino acid single-pass membrane protein belonging to the ARM family of proteins and may play a role in signal transduction. The function of this protein is unknown at this time.Microarray data show that ARMCX6 is highly expressed during earliest stages of spermatogenesis in mice.