Bromodomain, Testis Specific (BRDT)

BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Two transcript variants encoding the same protein have been found for this gene.A study of cDNA clones indicated that the gene encodes a protein of 947 amino acids with extensive homology to RING3 and to the Drosophila developmental gene fsh. Similar to these proteins, it possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation..