COMM Domain Containing Protein 7 (COMMD7)

COMMD7 is expressed at high level, 3.1 times the average gene in this release. COMMD7 contains 16 different introns. Transcription produces 10 alternatively spliced mRNAs. There are 2 probable alternative promotors, 2 non overlapping alternative last exons and 3 validated alternative polyadenylation sites . The mRNAs appear to differ by truncation of the 5""" end, truncation of the 3""" end, presence or absence of 5 cassette exons, overlapping exons with different boundaries, alternative splicing or retention of 3 introns. There are 2 articles specifically referring to this gene in PubMed. Proteins are expected to localize in various compartments (cytoplasm, mitochondrion). This gene"""s in vivo function is yet unknown.