Calcium Channel, Voltage Dependent, Gamma Subunit 6 (CACNg6)

CACNg6 represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two similar gamma subunit-encoding genes.The deduced 260-amino acid CACNG6 protein contains 4 transmembrane segments and a highly conserved N-glycosylation site in the first extracellular loop. It has a relatively long N terminus compared with the other CACNG proteins. RT-PCR analysis of 24 adult and fetal tissues detected expression of CACNG6 in all tissues tested except heart, placenta, and colon.