Coiled Coil Domain Containing Protein 90B (CCDC90B)

CCDC90B is located on chromosome 11 in humans. This protein is characterized by the presence of a domain of unknown function, DUF1640. This domain is a characteristic of the entire protein with the exception of the first twenty-three amino acid residues - MNSRQAWRLFLSQGRGDRWVSRP - which are a mitochondrial targeting site and cleaved.The protein has seven predicted alpha helices, a characteristic of coiled-coil proteins.CCDC90B is predicted to be a mitochondrial protein with no transmembrane spans or segments. It is predicted to contain at least three specific phospohorylation sites: Protein Kinase C Phosphorylation sites, Casein Kinase II Phosphorylation sites, and cAMP/cGMP Dependant Phosphorylation sites.