FERM Domain Containing Protein 1 (FRMD1)

FRMD1, Contains 1 FERM domain. FRMD1 is moderately expressed, only 26.8% of the average gene in this release. The gene contains 24 different introns. Transcription produces 8 different mRNAs, 7 alternatively spliced variants and 1 unspliced form. There are 3 probable alternative promotors, 2 non overlapping alternative last exons and 5 validated alternative polyadenylation sites. The mRNAs appear to differ by truncation of the 5""" end, truncation of the 3""" end, presence or absence of 5 cassette exons, overlapping exons with different boundaries, alternative splicing or retention of 5 introns. Isoform FRMD1.dApr07 is annotated using as Met a Kozak-compatible.TTGg start, thereby gaining 128 amino acids N-terminal to the first AUG Proteins are expected to have molecular function (binding) and to localize in various compartments.