Family With Sequence Similarity 49, Member A (FAM49A)

Family with sequence similarity 49, member A is a protein encoded by the FAM49A gene. Fam49A is located on human chromosome 2, at 2p24.3. It has 1512 base pairs in the reference sequence mRNA transcript.The Fam49A gene product is a 323 amino acid protein. The protein contains two domains: Residues 15-319 comprise the "Domain of Unknown Function 1394". Residues 67->281 comprise the "Cytoplasmic Fragile X Interacting Superfamily" region.The gene contains 23 different gt-ag introns. Transcription produces 17 different mRNAs, 14 alternatively spliced variants and 3 unspliced forms. There are 5 probable alternative promotors, 3 non overlapping alternative last exons and 7 validated alternative polyadenylation sites .