Family With Sequence Similarity 78, Member B (FAM78B)

Family With Sequence Similarity 78, Member B (FAM78B) belongs to the FAM78 family. Fam78 comprises a family of genes conserved across Trypanosoma at a single, tandemyl-arrayed locus. All genes have multiple transmembrane domains, and some copies predicted signal peptides. The Bayesian phylogram was estimated from a multiple nucleotide sequence alignment of 612 characters, using MrBayes under default settings. The tree is rooted with T. cruzi sequences. Selected nodes are supported by posterior probabilities and non-parametric bootstraps generated from a maximum likelihood analysis under a GTR+ model. In plain language, a transmembrane protein (TP) is a protein that goes from one side of a membrane through to the other side of the membrane.