Inhibitory Subunit Of NF Kappa B Delta (IkBd)

Inhibitory Subunit Of NF Kappa B Delta belongs to the NF-kappa-B inhibitor family.May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR- induced negative selection of thymocytes (By similarity).Tissue expression: blood; brain; embryonic tissue; eye; heart; intestine; kidney; lung; lymph node; mammary gland; ovary; pharynx; placenta; stomach; testis; thyroid; tonsil; breast (mammary gland) tumor; colorectal tumor; gastrointestinal tumor; germ cell tumor; head and neck tumor; leukemia; lung tumor; normal; ovarian tumor; embryoid body; fetus; adult; Interacts with NFKB1, RELA and RELB; in the nucleus