Kinesin Family, Member 7 (KIF7)

By database searching using Drosophila Cos2 and mouse Kif7 as probes, Katoh and Katoh (2004) identified full-length KIF7. The deduced 1,343-amino protein shares 43.6% amino acid identity with KIF27 (611253) and 61.6% identity with KIF27 over the kinesin motor domain.Katoh and Katoh (2004) determined that the KIF7 gene contains at least 19 exons.By genomic sequence analysis, Katoh and Katoh (2004) mapped the KIF7 gene to chromosome 15q26.1.KIF7 and KIF27 also share an additional region of high homology, which the authors called the KIF7-KIF27 homologous (KIF727H) domain. EST database analysis showed KIF7 mRNA expression in embryonic stem cells, melanotic melanoma, and Jurkat T cells.