LIM And Cysteine Rich Domains Protein 1 (LMCD1)

Dyxin contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. Expression of this gene has been detected in most tissues, with highest expression in skeletal muscle. Transcript variants utilizing alternative polyA signals have been observed. The predicted 365-amino acid LMCD1 protein contains a novel cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. LMCD1 shares significant amino acid sequence identity with mouse Tes1, mouse Tes2, human LMO6 , and the human triple-LIM domain protein.