Mitochondrial Assembly Of Ribosomal Large Subunit Protein 1 (MALSU1)

C7orf30 is highly conserved in mammals and shows some conservation in other eukaryotes and archaea. Examples of mammalian conservation are given below using the ALIGN tool from the San Diego Supercomputer Center Biology Workbench. While the function of the protein is not conclusive, it is predicted that it interacts in some way with the mitochondria of cells. This DUF is from position 93 to 194 on the human protein and comprises 43.2% of the sequence. This conserved domain is also present in the plant gene iojap, a pattern-striping gene in maize. DUF143 has also been shown to interact with UFD1, tRNA synthetases class.  C7ORF30 is located on chromosome 7 in humans and runs from 23,305,465 to 23,315,705.