NudC Domain Containing Protein 2 (NUDCD2)

NUDCD2, Contains 1 CS domain. NUDF and NUDC directly interacted in yeast two-hybrid experiments via NUDF"""s WD40 domain. NUDC-green fluorescent protein (NUDC-GFP) was localized to immobile dots in the cytoplasm and at the hyphal cortex, some of which were spindle pole bodies (SPBs). NUDC directly interacted with NUDF at SPBs at different stages of the cell cycle. BNFA was dispensable for growth and for nuclear migration. GFP-BNFA fusions localized to SPBs at different stages of the cell cycle. This localization depended on NUDF, since the loss of NUDF resulted in the cytoplasmic accumulation of BNFA. BNFA did not bind to NUDC in a yeast two-hybrid assay.