PiggyBac Transposable Element Derived Protein 1 (PGBD1)

PGBD1 is a member of the piggyBac family of proteins, found in diverse animals, which are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. This gene product is specifically expressed in the brain, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.