Pleckstrin Homology Domain Containing Family G, Member 3 (PLEKHG3)

PLEKHG3, Contains 1 DH (DBL-homology) domain. The gene contains 23 different gt-ag introns. Transcription produces 8 different mRNAs, 7 alternatively spliced variants and 1 unspliced form. There are 4 probable alternative promotors, 2 non overlapping alternative last exons and 6 validated alternative polyadenylation sites. The mRNAs appear to differ by truncation of the 5""" end, truncation of the 3""" end, presence or absence of 3 cassette exons, overlapping exons with different boundaries, alternative splicing or retention of 2 introns. 716 bp of this gene are antisense to spliced gene SPTB, raising the possibility of regulated alternate expression. the gene has been proposed to participate in a process. Proteins are expected to have molecular function and to localize in intracellular.