Poly A Binding Protein Cytoplasmic 1 Like Protein (PABPC1L)

PABPC1L belongs to the polyadenylate-binding protein type-1 family. Recent linkage studies and association analyses indicate the presence of at least one type 2 diabetes susceptibility gene in human chromosome region 20q12-q13.1. The map currently provides near-continuous coverage between SGC32867 and WI-17676 .EST database searches and genomic sequence alignments of ESTs, mRNAs, and UniGene clusters enabled the annotation of the sequence interval with experimentally confirmed and putative transcripts. The combination of the BAC transcript map, YAC-to-BAC scaffold, and reference Human Genome Project sequence provides a powerful integrated resource for future genomic analysis of this region.