Ribosomal Protein L19 (RPL19)

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL19 encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L19E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.The wide distribution of the ribosomal protein genes throughout the human genome suggests that coordinate regulation of their expression in response to a cell"""s varying requirements for protein synthesis is not a result of cis-activation of chromosomal regions but is mediated by trans-acting factors.