SKI Family Transcriptional Corepressor 2 (SKOR2)

Corl2 expression was restricted to the central nervous system in both adult and embryonic stages. Corl2 is selectively expressed at high levels in the developing cerebellum, ventral metencephalon and myelencephalon at E12.5. In these brain regions, neural progenitors did not express Corl2 during the proliferative state but started to express it shortly after exit from the cell cycle. In the cerebellum, Corl2 was specifically expressed in PCs at the adult stage, and consistently, most Corl2(+) cells expressed PC markers, such as RORalpha and calbindin, at the late embryonic stage. Corl2(+) cells in the cerebellum did not express the GABAergic interneuron marker Pax2 at any of the developmental stages. Corl2 is a specific marker for PCs in the cerebellum from their emergence until the adult stage.