Solute Carrier Family 16, Member 14 (SLC16A14)

Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions.This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. MCT14 also known as SLC16A14, is a 510 amino acid multi-pass membrane protein that belongs to the MCT family and functions as a proton-linked monocarboxylate transporter, effectively catalyzing the rapid transport of monocarboxylates across the membrane. Multiple isoforms of MCT14 exist due to alternative splicing events.