Sorting Nexin 30 (SNX30)

SNX30, Belongs to the sorting nexin family.Contains 1 PX (phox homology) domain. Sorting nexins are a large group of proteins that are localized in the cytoplasm and have the potential for membrane association either through their lipid-binding PX domain (a phospholipid-binding motif) or through protein-protein interactions with membrane-associated protein complexes[2][3] Some members of this family have been shown to facilitate protein sorting.Sorting nexins either consist solely of a PX domain (eg SNX3) or have a modular structure made up of the PX and additional domains.A subgroup of sorting nexins (comprising, in humans, SNX1, SNX2, SNX4, SNX5, SNX6, SNX7, SNX8, SNX9, SNX18, SNX30, SNX32 and SNX33) possess a BAR domain at their C-terminus.