Stathmin 4 (STMN4)

STMN4, belongs to the stathmin family, encoding RB3, a protein related to stathmin, and in alterations to many tubulin isotype mRNAs.Cells differing in STMN1 genotype expressed different mRNA levels for the stathmin related protein STMN4 (RB3), with STMN/MEFs showing upregulation of STMN4, by either microarray or RT-PCR analysis. STMN4 not expression in MEFs with antibodies currently available, indicating that STMN4 protein is likely present at a low level in these cells. the expression of other MT destabilizers are reduced in STMN1/MEFs, making it unlikely that cells compensate for loss of STMN1 through expression of STMN4 or other MT destabilizers.