Syntaxin 10 (STX10)

Syntaxin-10 (STX10) is found in most vertebrates (including humans) but is noticeably absent from mice. As with other SNARE proteins, STX10 facilitates vesicle fusion and thus is important for intracellular trafficking of proteins and other cellular components. More specifically, STX10 has been implicated in endosome to Golgi trafficking of the mannose 6-phosphate receptor and glucose transporter type 4.STX10 has been detected in the trans-Golgi network (TGN) by immunofluorescence.STX10 is structurally classified as a q-SNARE (contributes a glutamine (Q) residue in the formation of the assembled core SNARE complex) and is functionally classified as a t-SNARE (or target-SNARE which is located in the membranes of target compartments).